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Article: The Truth About Seed Oils in Skincare (It’s Not What You’ve Heard in Nutrition)

The Truth About Seed Oils in Skincare (It’s Not What You’ve Heard in Nutrition)

The Truth About Seed Oils in Skincare (It’s Not What You’ve Heard in Nutrition)

Rethinking Plant Oils in Skincare

Fatty acids and plant oils are having a moment in skincare conversations, often wrapped up in bigger discussions about health, nutrition, and inflammation. It makes sense. We’re all trying to understand what supports the body and what doesn’t, and skin care is no exception. But skin has its own physiology, its own needs, and its own language, and it’s worth meeting it there.

The skin barrier is not just a surface to coat or seal. It is a living system made up of cells and lipids that work together to maintain hydration, regulate inflammation, and protect us from the world around us. Fatty acids are a natural and essential part of that system. They help shape the structure of the barrier itself and influence how skin responds to stress, sensitivity, and change.

Plant oils, including many seed oils, are simply one way fatty acids show up in topical care. Their value depends on their composition, how they are processed, and how they are formulated alongside other supportive ingredients. When chosen with intention, these oils can offer meaningful support to the skin barrier, particularly for skin that feels dry, reactive, or out of balance.

This piece is an invitation to slow down and look more closely at how fatty acids actually function in the skin. By understanding the roles of omega 3, 6, and 9 fatty acids, and how they contribute to barrier health, we can approach plant oils with more clarity and confidence. Skin care becomes less about avoiding ingredients and more about working with the body’s natural design.

Why Fatty Acids Matter at the Cellular Level

Fatty acids are not niche or specialized molecules. They are woven into human physiology at every level. We encounter them in food, they circulate through the bloodstream, and they are built directly into our cells and tissues. At the cellular level, fatty acids help form membranes, participate in signaling, and influence how cells respond to stress, inflammation, and hormonal cues. They are part of how tissues maintain structure, communicate, and adapt.

Most discussions of fatty acids focus on diet and long-term metabolic health, which has shaped how we tend to think about them. That research has been important, but it has also shown something quieter and more nuanced: fatty acids are not interchangeable. Even within the same broad category, individual fatty acids behave differently, shaping membrane structure and cellular activity in distinct ways. Their effects depend on context, location, and how they are used by the tissue they are supporting.

This distinction becomes especially relevant when we turn our attention to the skin. In this tissue, fatty acids are not acting as fuel or circulating signals. They are structural. They are part of the lipid framework that helps hold the barrier together, influencing how skin retains moisture, tolerates environmental stress, and regulates inflammatory responses. The balance and organization of these fatty acids help determine whether the barrier feels resilient or easily disrupted.

Looking at fatty acids through this lens invites a more functional way of thinking about topical care. Rather than grouping fats into broad categories or relying on simplified rules, it becomes more useful to consider how specific fatty acids interact with the skin itself. This keeps the focus where it belongs: on supporting barrier integrity and working with the skin’s natural design.

The Skin Barrier as a Living Interface

Biological barriers exist wherever the body meets the outside world. Their role is not only to shield us from physical injury, pathogens, and environmental stressors, but also to regulate exchange, maintain internal balance, and support survival in changing conditions. The skin is one of the most complex and vital of these barriers. It helps prevent excessive water loss, contributes to thermoregulation, and provides ongoing protection from ultraviolet radiation, microbes, and environmental toxins.

This work is not carried out by a single structure or layer. The skin barrier is multifaceted, relying on the physical permeability barrier of the stratum corneum, the immune activity of the epidermis and dermis, and the presence of a diverse microbial community at the surface. Together, these layers form a responsive system that adapts to the environment rather than
simply resisting it.

Lipids sit at the center of this system. The skin is not only rich in lipids, it carries out a form of lipid metabolism that is distinct from other tissues in the body. A wide range of bioactive lipids are involved in building, maintaining, and regulating the barrier, including ceramides, cholesterol, free fatty acids, and lipid-derived mediators that influence inflammation and immune signaling. These lipids actively shape how the barrier repairs itself, responds to stress, and communicates with both immune cells and resident microbes.

The Stratum Corneum and the Lipid Matrix

At the outermost surface of the skin, the stratum corneum forms the foundation of the physical permeability barrier. It is made up of terminally differentiated skin cells, called corneocytes, arranged within a highly organized lipid matrix. Each corneocyte is wrapped in a protein-rich envelope that provides strength and structure, while a lipid layer bound to its surface helps anchor and organize the surrounding fats. Between these cells, lamellar sheets of ceramides, cholesterol, and free fatty acids come together to create a carefully regulated barrier that limits water loss and controls what is able to pass into and out of the skin.

This structure is often explained using the familiar “brick and mortar” analogy, but that image only hints at what is actually happening. In healthy skin, these lipid layers are arranged in precise, ordered patterns that allow the barrier to remain both flexible and resilient. When lipid composition shifts, whether due to inflammation, illness, aging, or environmental stress, that organization begins to change. The result is a barrier that is less efficient and more easily disrupted, often experienced as dryness, sensitivity, or reactivity.

Because the epidermis depends on a steady supply of essential fatty acids, particularly linoleic and alpha-linolenic acid, skin health reflects an ongoing balance between internal and external influences. Nutrition, environmental exposures, lifestyle factors, inflammatory conditions, hormonal changes, and age all shape the quality and resilience of the barrier. Over time, these pressures can leave the skin more fragile, slower to recover, and more prone to irritation. 

Seeing the skin barrier as a lipid-driven, living interface invites a shift in how we think about topical care. Support is no longer just about adding moisture or avoiding certain ingredients. It becomes about working with the skin’s underlying biology. Lipids, including fatty acids, sit at the center of this process, influencing not only how the skin feels, but how it functions, adapts, and protects itself over time.

Plant Oils as Sources of Fatty Acids

Plant oils vary widely in their fatty acid composition, and those differences matter at a biological level. Oils are not inert or interchangeable. Each one carries a distinct profile of fatty acids that shapes how it interacts with the skin barrier, particularly the lipid matrix of the stratum corneum. This is why two oils can feel similar at first touch, yet behave very differently on the skin over time.

At a biochemical level, fatty acids differ in chain length, degree of saturation, and structure, all of which influence how they integrate into the skin’s lipid layers. Within the stratum corneum, free fatty acids sit alongside ceramides and cholesterol in carefully organized lamellar structures that help regulate permeability and water retention. Research on barrier physiology shows that when this lipid organization is disrupted, barrier function suffers. The issue is often not a lack of moisture alone, but a breakdown in how these lipids are arranged and maintained, which can
leave skin more sensitive and reactive.

Fatty Acid Composition and Barrier Function

Many plant-derived oils, including a number of seed oils, are naturally rich in linoleic acid, an essential fatty acid with a clear structural role in the epidermal barrier. Linoleic acid is incorporated into acylceramides, a class of skin-specific ceramides that help form the lamellar lipid architecture of healthy skin. When linoleic acid availability is reduced, barrier integrity begins to weaken and transepidermal water loss increases, a relationship that shows up consistently in both experimental research and clinical observations of compromised skin.

Other fatty acids commonly found in plant oils interact with the barrier in different ways. Oleic acid, for example, can increase lipid fluidity and permeability. In some contexts this may support absorption or softness, while in others it can disrupt barrier organization if not balanced carefully. Alpha-linolenic acid and other polyunsaturated fatty acids play a different role, serving as precursors to lipid mediators involved in inflammatory signaling within the skin. These effects are not fixed or universal. They depend on the surrounding lipid environment and the overall condition of the barrier.

This is where topical use diverges from dietary frameworks. In nutrition science, plant oils are often discussed in terms of how efficiently their fatty acids are converted into longer-chain polyunsaturated fatty acids within the body. The skin does not rely on these conversion pathways in the same way. When applied topically, fatty acids act locally within an already lipid rich tissue, contributing directly to barrier structure, signaling, and microbial balance rather than systemic fatty acid pools.

For this reason, the value of a plant oil in skincare cannot be reduced to whether it is labeled a seed oil or to its fatty acid ratios in isolation. What matters is how its fatty acid profile aligns with the needs of the skin barrier, how stable the oil is, and how it is formulated alongside other lipids that support lamellar organization. When these pieces come together, plant oils function as biologically relevant tools for barrier support rather than passive emollients.

A Barrier-Centered Approach to Facial Oils: Eclipse Skin Elixir

When skin is sensitive or easily reactive, the goal of topical care shifts. It becomes less about adding more products and more about choosing formulations that respect the biology of the skin barrier. Eclipse Skin Elixir was created with this exact context in mind. 

Rather than relying on a single hero oil, Eclipse combines a carefully balanced blend of botanical seed oils chosen for their fatty acid profiles and their compatibility with sensitive skin. Each oil contributes structurally and functionally to barrier support, offering nourishment without occlusion or heaviness. This matters, because compromised skin often struggles not with dryness alone, but with lipid imbalance and impaired barrier organization.

Hemp seed oil forms a foundational part of the formula, supplying both omega-3 and omega-6 fatty acids in proportions that support barrier integrity without clogging pores. Black currant seed oil adds gamma-linolenic acid (GLA), a fatty acid long studied for its role in inflammatory pathways and its relevance in conditions characterized by redness and irritation. Together, these oils help reinforce the lipid matrix of the stratum corneum rather than simply coating the surface of the skin.

Supporting botanicals such as schisandra fruit CO₂ extract and sea buckthorn CO₂ oil contribute antioxidant and adaptogenic properties that align with the needs of stressed or reactive skin. Sea buckthorn, in particular, provides carotenoids and lipid-soluble antioxidants that support skin renewal while remaining lightweight in feel. Meadowfoam, cacay, strawberry seed, and oat seed oils round out the blend, contributing stability, softness, and additional barrier-supportive lipids.

What makes Eclipse especially well suited for sensitive or acne-prone skin is not just what it contains, but how it is formulated. The oil remains lightweight and fast-absorbing, avoiding the occlusive heaviness that can exacerbate congestion or irritation. This allows it to be used daily, even by those who have struggled to tolerate facial oils in the past.

For individuals navigating sensitive skin, formulation matters as much as ingredients. Eclipse Skin Elixir reflects a barrier-centered approach to skincare, one that prioritizes lipid balance, structural support, and calm over quick fixes or aggressive actives. For skin that has “been through it,” this kind of thoughtful formulation can make the difference between ongoing reactivity and gradual restoration of balance.

— Agy | The Buffalo Herbalist

Agy is an herbalist with an MSc in Herbal Medicine and an MD (non-practicing), and a doctoral student in integrative health. Her work focuses on the intersection of traditional herbal medicine, whole-body wellness, and skin health.

Learn more at The Buffalo Herbalist
@thebuffaloherbalist
The Buffalo Herbalist Substack

Bibliography:
Rizzo, G., Baroni, L., & Lombardo, M. (2023). Promising Sources of Plant-Derived Polyunsaturated Fatty Acids: A Narrative Review. International Journal of Environmental Research and Public Health, 20(3), 1683. https://doi.org/10.3390/ijerph20031683

Jain, P., & Lingwan, M. (2025). No more fishes: Plants as a bio-factory for omega-3 fatty acid. PLANT PHYSIOLOGY, 200(1). https://doi.org/10.1093/plphys/kiaf679

Nicolaou, A., & Kendall, A. C. (2024). Bioactive lipids in the skin barrier mediate its functionality in health and disease. Pharmacology & Therapeutics, 260, 108681. https://doi.org/10.1016/j.pharmthera.2024.108681

Szabó, É. (2025). Dietary fatty acids and metabolic health. Nutrients, 17(15), 2512. https://doi.org/10.3390/nu17152512

Calder, P. C. (2015). Functional roles of fatty acids and their effects on human health. Journal of Parenteral and Enteral Nutrition, 39(1S), 18S-32S. https://doi.org/10.1177/0148607115595980

Laurindo, L. F., Laurindo, L. F., Laurindo, L. F., Laurindo, L. F., Rodrigues, V. D., Da Silva Camarinha Oliveira, J., Boaro, B. L., Araújo, A. C., Guiguer, E. L., Detregiachi, C. R. P., Catharin, V. M. C. S., Chagas, E. F. B., Catharin, V. C. S., Direito, R., & Barbalho, S. M. (2025). Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinical studies. Frontiers in Nutrition, 12, 1502815. https://doi.org/10.3389/fnut.2025.1502815

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